An aphid symbiont confers protection against a specialized RNA virus, another increases vulnerability to the same pathogen December 2, 2022
MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques November 24, 2022
Avoiding clinical trial failures in neglected tropical diseases: The example of Chagas disease November 14, 2022
Evaluation of delayed LNFPIII treatment initiation protocol on improving long-term behavioral and neuroinflammatory pathology in a mouse model of Gulf War Illness November 8, 2022
Gastrointestinal helminths increase Bordetella bronchiseptica shedding and host variation in supershedding November 8, 2022
Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure October 31, 2022
Assessing seroprevalence and associated risk factors for multiple infectious diseases in Sabah, Malaysia using serological multiplex bead assays October 25, 2022
Spindly is a nucleocytosolic O-fucosyltransferase in Dictyostelium and related proteins are widespread in protists and bacteria October 17, 2022
Hypothesis-generating proteome perturbation to identify NEU-4438 and acoziborole modes of action in the African Trypanosome October 7, 2022
Liver-stage fate determination in Plasmodium vivax parasites: Characterization of schizont growth and hypnozoite fating from patient isolates September 23, 2022
MICU1 and MICU2 potentiation of Ca2+ uptake by the mitochondrial Ca2+ uniporter of Trypanosoma cruzi and its inhibition by Mg2 September 21, 2022
The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection September 21, 2022
Streamlining sporozoite isolation from mosquitoes by leveraging the dynamics of migration to the salivary glands September 13, 2022
Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates September 5, 2022
Multiple endocrine factors regulate nutrient mobilization and storage in Aedes aegypti during a gonadotrophic cycle September 2, 2022
Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets August 25, 2022
Temporal and thermal profiling of the Toxoplasma proteome implicates parasite Protein Phosphatase 1 in the regulation of Ca 2+-responsive pathways August 17, 2022
Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions August 3, 2022
Oxygen-dependent regulation of E3(SCF)ubiquitin ligases and a Skp1-associated JmjD6 homolog in development of the social amoeba Dictyostelium August 3, 2022
A Krüppel-like factor is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians July 15, 2022
Quantitative 3D Imaging of Trypanosoma cruzi-Infected Cells, Dormant Amastigotes, and T Cells in Intact Clarified Organs June 23, 2022
Multiplex Serology for Measurement of IgG Antibodies Against Eleven Infectious Diseases in a National Serosurvey: Haiti 2014-2015 June 9, 2022
Disruption of Toxoplasma gondii-Induced Host Cell DNA Replication Is Dependent on Contact Inhibition and Host Cell Type May 19, 2022
Small and intermediate size structural RNAs in the unicellular parasite Cryptosporidium parvum as revealed by sRNA-seq and comparative genomics May 10, 2022
Polymorphic Molecular Signatures in Variable Regions of the Plasmodium falciparum var2csa DBL3x Domain Are Associated with Virulence in Placental Malaria April 28, 2022
Improving in vitro continuous cultivation of Plasmodium cynomolgi, a model for P. vivax April 22, 2022
Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp April 18, 2022
Ad libitum consumption of protein- or peptide-sucrose solutions stimulates egg formation by prolonging the vitellogenic phase of oogenesis in anautogenous mosquitoes April 12, 2022
Anopheles gambiae strain (Ag55) cultured cells originated from Anopheles coluzzii and are phagocytic with hemocyte-like gene expression March 31, 2022
Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12) March 30, 2022
Development and Introduction of the Filariasis Test Strip: A New Diagnostic Test for the Global Program to Eliminate Lymphatic Filariasis March 15, 2022
In Vivo Efficacy of SQ109 against Leishmania donovani, Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites March 14, 2022
Insulin-like peptide 3 stimulates hemocytes to proliferate in anautogenous and facultatively autogenous mosquitoes March 8, 2022
Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro February 24, 2022
Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials February 23, 2022
Activity-based Crosslinking to Identify Substrates of Thioredoxin-domain Proteinsin Malaria Parasites February 20, 2022
Protozoan phagotrophy from predators to parasites: An overview of the enigmatic cytostome-cytopharynx complex of Trypanosoma cruzi February 17, 2022
Differential Growth Rates and In Vitro Drug Susceptibility to Currently Used Drugs for Multiple Isolates of Naegleria fowleri February 9, 2022
Insulin-like peptide 3 stimulates hemocytes to proliferate in anautogenous and facultatively autogenous mosquitoes February 7, 2022
CRISPR/Cas9-induced disruption of Bodo saltans paraflagellar rod-2 gene reveals its importance for cell survival January 31, 2022
Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity January 14, 2022
The complete genome of Chelonus insularis reveals dynamic arrangement of genome components in parasitoid wasps that produce bracoviruses January 5, 2022
Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting December 24, 2021
Bracoviruses, ichnoviruses, and virus-like particles from parasitoid wasps retain many features of their virus ancestors December 22, 2021
Toxoplasma bradyzoites exhibit physiological plasticity of calcium and energy stores controlling motility and egress December 3, 2021
Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: a spatiotemporal modelling study December 2, 2021
A Target Site Mutation Associated With Diamide Insecticide Resistance in the Diamondback Moth Plutella xylostella (Lepidoptera: Plutellidae) is Widespread in South Georgia and Florida Populations November 26, 2021
Diagnostic Characteristics of Lactate Dehydrogenase on a Multiplex Assay for Malaria Detection Including the Zoonotic Parasite Plasmodium knowlesi November 15, 2021
Diagnostics to support elimination of lymphatic filariasis-Development of two target product profiles November 15, 2021
Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveals expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions November 11, 2021
Evolutionary genomics of APSE: a tailed phage that lysogenically converts the bacterium Hamiltonella defensa into a heritable protective symbiont of aphids November 10, 2021
The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design November 4, 2021
The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions November 2, 2021
Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria November 2, 2021
Control and elimination of lymphatic filariasis in Oceania: Prevalence, geographical distribution, mass drug administration, and surveillance in Samoa, 1998-2017 October 27, 2021
Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro October 7, 2021
A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii October 4, 2021
Drug Target Validation of the Protein Kinase AEK1, Essential for Proliferation, Host Cell Invasion, and Intracellular Replication of the Human Pathogen Trypanosoma cruzi September 29, 2021
Unprotected water sources and low latrine coverage are contributing factors to persistent hotspots for schistosomiasis in western Kenya September 17, 2021
Delayed treatment with the immunotherapeutic LNFPIII ameliorates multiple neurological deficits in a pesticide-nerve agent prophylactic mouse model of Gulf War Illness July 10, 2021
Defense-Related Gene Expression Following an Orthotospovirus Infection Is Influenced by Host Resistance in Arachis hypogaea July 5, 2021
EdU Incorporation To Assess Cell Proliferation and Drug Susceptibility in Naegleria fowleri June 17, 2021
Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts June 14, 2021
Calcium signaling through a Transient Receptor Channel is important for Toxoplasma gondii growth June 9, 2021
Trypanosoma cruzi Letm1 is involved in mitochondrial Ca 2+ transport, and is essential for replication, differentiation, and host cell invasion June 7, 2021
Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model June 5, 2021
Lack of detectable short-term effects of a single dose of ivermectin on the human immune system June 5, 2021
Immune exhaustion in chronic Chagas disease: Pro-inflammatory and immunomodulatory action of IL-27 in vitro June 1, 2021
TbVps41 regulates trafficking of endocytic but not biosynthetic cargo to lysosomes of bloodstream forms of Trypanosoma brucei May 27, 2021
A Comparison of Two Structurally Related Human Milk Oligosaccharide Conjugates in a Model of Diet-Induced Obesity May 20, 2021
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1 H)-Quinolones with Single Dose Cures May 12, 2021
Toll9 from Bombyx mori functions as a pattern recognition receptor that shares features with Toll-like receptor 4 from mammals May 10, 2021
Lacto-N-fucopentaose-III (LNFPIII) ameliorates acute aberrations in hippocampal synaptic transmission in a Gulf War Illness animal model May 4, 2021
A novel fragmented mitochondrial genome in the protist pathogen Toxoplasma gondii and related tissue coccidia April 27, 2021
Baseline Mapping of Neglected Tropical Diseases in Africa: The Accelerated WHO/AFRO Mapping Project April 26, 2021
Casein kinase TbCK1.2 regulates division of kinetoplast DNA, and movement of basal bodies in the African trypanosome April 16, 2021
Survival of Salmonella and Shiga Toxin-producing Escherichia coli and Changes in Indigenous Microbiota During Fermentation of Kombucha Made from Home-brewing Kits April 14, 2021
EdU incorporation to assess cell proliferation and drug susceptibility in Naegleria fowleri April 12, 2021
Riboflavin instability is a key factor underlying the requirement of a gut microbiota for mosquito development April 9, 2021
Estimating true prevalence of Schistosoma mansoni from population summary measures based on the Kato-Katz diagnostic technique April 6, 2021
Mitochondrial Pyruvate Carrier Subunits Are Essential for Pyruvate-Driven Respiration, Infectivity, and Intracellular Replication of Trypanosoma cruzi April 6, 2021
Synthesis of Mono- and Bisperoxide-Bridged Artemisinin Dimers to Elucidate the Contribution of Dimerization to Antimalarial Activity April 1, 2021
Ca2+ entry at the plasma membrane and uptake by acidic stores is regulated by the activity of the V‐H+‐ATPase in Toxoplasma gondii April 1, 2021
High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA March 31, 2021
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba March 24, 2021
Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency March 17, 2021
Deletion of a Golgi protein in Trypanosoma cruzi reveals a critical role for Mn2+ in protein glycosylation needed for host cell invasion and intracellular replication March 15, 2021
RGS10 physically and functionally interacts with STIM2 and requires store-operated calcium entry to regulate proinflammatory gene expression in microglia March 8, 2021
Reduced Trypanosoma cruzi-specific humoral response and enhanced T cell immunity after treatment interruption with benznidazole in chronic Chagas disease March 7, 2021
Whole blood and blood components from vertebrates differentially affect egg formation in three species of anautogenous mosquitoes February 24, 2021
Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthelmintic resistance on a sheep farm February 18, 2021
MdBVe46 is an envelope protein that is required for virion formation by Microplitis demolitor bracovirus February 16, 2021
A redox-active crosslinker reveals an essential and inhibitable oxidative folding network in the endoplasmic reticulum of malaria parasites February 3, 2021
