Michael Strand Tag

Toll9 from Bombyx mori functions as a pattern recognition receptor that shares features with Toll-like receptor 4 from mammals

Posted on May 10, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Toll/Toll-like receptors (TLRs) are key regulators of the innate immune system in both invertebrates and vertebrates. However, while mammalian TLRs directly recognize pathogen-associated molecular patterns, the insect Toll pathway is thought to be primarily activated by binding...

Riboflavin instability is a key factor underlying the requirement of a gut microbiota for mosquito development

Posted on Apr 9, 2021 in publications

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We previously determined that several diets used to rear Aedes aegypti and other mosquito species support the development of larvae with a gut microbiota but do not support the development of axenic larvae. In contrast, axenic larvae have been shown to develop when fed other diets. To...

Whole blood and blood components from vertebrates differentially affect egg formation in three species of anautogenous mosquitoes

Posted on Feb 24, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Background: Most female mosquitoes are anautogenous and must blood feed on a vertebrate host to produce eggs. Prior studies show that the number of eggs females lay per clutch correlates with the volume of blood ingested and that...

MdBVe46 is an envelope protein that is required for virion formation by Microplitis demolitor bracovirus

Posted on Feb 16, 2021 in publications

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Bracoviruses (BVs) are endogenized nudiviruses that braconid parasitoid wasps have coopted for functions in parasitizing hosts. Microplitis demolitor is a braconid wasp that produces Microplitis demolitor bracovirus (MdBV) and parasitizes the larval stage of the moth Chrysodeixis includens. Some BV core genes are homologs of genes also present...

Gene content evolution in the arthropods

Posted on Jan 23, 2020 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Abstract BACKGROUND: Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes...

Predaceous Toxorhynchites mosquitoes require a living gut microbiota to develop

Posted on Jan 22, 2020 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Most species of mosquitoes are detritivores that feed on decaying plant and animal materials in their aquatic environment. Studies of several detritivorous mosquito species indicate that they host relatively low diversity communities of microbes that are acquired...

The genomes of two parasitic wasps that parasitize the diamondback moth

Posted on Nov 21, 2019 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Background Parasitic insects are well-known biological control agents for arthropod pests worldwide. They are capable of regulating their host’s physiology, development and behaviour. However, many of the molecular mechanisms involved in host-parasitoid interaction remain unknown. Results We sequenced the genomes...

Preferential infectivity of entomopathogenic nematodes in an envenomed host

Posted on Jul 12, 2019 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Entomopathogenic nematodes and parasitoid wasps are used as biological control agents for management of insect pests such as the Indian meal moth, Plodia interpunctella. The parasitoid wasp Habrobracon hebetor injects a paralytic venom into P. interpunctella larvae before laying eggs. A previous study...

Toll family members bind multiple Spätzle proteins and activate antimicrobial peptide gene expression in Drosophila

Posted on May 14, 2019 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] [caption id="attachment_5507" align="aligncenter" width="600"] This illustration depicts a dorsal view of the “common” fruit fly, or “vinegar” fly, Drosophila melanogaster.Courtesy of Public Health Image Library[/caption] The Toll signaling pathway in Drosophila melanogaster regulates several immune-related functions, including the...

What’s Bugging MICHAEL STRAND?

Posted on May 13, 2019 in CTEGD Blog

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] by Leigh Beeson When warm weather approaches, so do pesky little bloodsucking pests. The unassuming mosquito may be smaller than a dime, but it packs a serious punch, killing more people each year than any other animal. And with average...

Michael Strand Tag

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