Author: Donna Huber

The Inositol Pyrophosphate Biosynthetic Pathway of Trypanosoma cruzi

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Inositol phosphates (IPs) are phosphorylated derivatives of myo-inositol involved in the regulation of several cellular processes through their interaction with specific proteins. Their synthesis relies on the activity of specific kinases that use ATP as phosphate donor....

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The IP 3 receptor and Ca 2+ signaling in trypanosomes

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Trypanosoma cruzi, and the T. brucei group of parasites cause neglected diseases that affect millions of people around the world. These unicellular microorganisms have complex life cycles involving an insect vector and a mammalian host. Both groups of pathogens...

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Roberto Docampo, a leading researcher in the study of acidocalcisomes in trypanosomatids

Affinity‐based proteomics reveals novel targets of inositol pyrophosphate (5‐IP7)‐dependent phosphorylation and binding in Trypanosoma cruzi replicative stages

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Diphosphoinositol-5-pentakisphosphate (5-PP-IP5 ), also known as inositol heptakisphosphate (5-IP7 ), has been described as a high-energy phosphate metabolite that participates in the regulation of multiple cellular processes through protein binding or serine pyrophosphorylation, a post-translational modification involving a β-phosphoryl...

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Evolution of the monitoring and evaluation strategies to support the World Health Organization’s Global Programme to Eliminate Lymphatic Filariasis

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]The Global Programme to Eliminate Lymphatic Filariasis (GPELF) was established with the ambitious goal of eliminating LF as a public health problem. The remarkable success of the GPELF over the past 2 decades in carrying out its...

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Ortega

In the News: Ynes Ortega’s work on Cyclospora is featured

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Ynes Ortega's work on the pathogen Cyclospora cayetanensis is featured in Vegetable Growers News, Produce Processing, and Food Safety News.[/vc_column_text][/vc_column][vc_column width="1/3"][vc_widget_sidebar sidebar_id="News recent post"][/vc_column][/vc_row]...

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Fall 2020 Newsletter

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Learn about our research activities, faculty honors, new grants, and trainees from the summer and fall. [button size='large' style='' text='Read Now' icon='' icon_color='BA0C2F' link='http://ctegd.uga.edu/docs/ctegd/newsletter_Dec_2020_video.pdf' target='_self' color='' hover_color='' border_color='' hover_border_color='' background_color='' hover_background_color='' font_style='' font_weight='' text_align='center' margin=''] [/vc_column_text][/vc_column][vc_column width="1/3"][vc_widget_sidebar sidebar_id="News recent...

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Roberto Docampo, a leading researcher in the study of acidocalcisomes in trypanosomatids

Different Sensitivity of Control and MICU1- and MICU2-Ablated Trypanosoma cruzi Mitochondrial Calcium Uniporter Complex to Ruthenium-Based Inhibitors

The mitochondrial Ca2+ uptake in trypanosomatids shares biochemical characteristics with that of animals. However, the composition of the mitochondrial Ca2+ uniporter complex (MCUC) in these parasites is quite peculiar, suggesting lineage-specific adaptations. In this work, we compared the inhibitory activity of ruthenium red (RuRed) and Ru360, the...

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Rick Tarleton elected AAAS Fellow

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] [caption id="attachment_6140" align="aligncenter" width="600"] Photo credit: Andrew Tucker[/caption] University of Georgia researcher Rick Tarleton has been elected as a 2020 American Association for the Advancement of Science (AAAS) Fellow by the AAAS Council “for distinguished contributions to the...

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Rick Tarleton

Stronger, less frequent treatments could cure Chagas disease [video]

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text][vc_video link='https://youtu.be/t5aNtmZON6o'] Video by UGA Research Communications Read more about the study.[/vc_column_text][vc_empty_space][/vc_column][vc_column width="1/3"][vc_widget_sidebar sidebar_id="News recent post"][/vc_column][/vc_row]...

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Jessica Kissinger

Jessica Kissinger elected ASTMH Fellow

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] [caption id="attachment_4775" align="aligncenter" width="600"] Jessica Kissinger (Photo by Peter Frey)[/caption] University of Georgia geneticist Jessica Kissinger has been elected a 2020 American Society of Tropical Medicine and Hygiene Fellow. Kissinger is a Distinguished Research Professor in the Department of Genetics, part of...

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