Author: Donna Huber

Ph.D. candidate Ale Villegas and advisor Vasant Muralidharan receive Gilliam Graduate Fellowship Award

Posted on Jul 28, 2021 in CTEGD Blog

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] [caption id="attachment_6635" align="aligncenter" width="600"] PhD Candidate Ale Villegas and Advisor Dr. Vasant Muralidharan (Photo Courtesy of Vasant Muralidharan)[/caption] Malaria’s connection to Georgia goes back to the colonial period. The Southeastern United States provided prime conditions for a thriving...

Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is a Bimodal Process

Posted on Jul 28, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous GPI-specific phospholipase C (GPI-PLC). However, GPI-PLC is...

Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

Posted on Jul 28, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Filariae are vector-borne nematodes responsible for an enormous burden of disease. Human lymphatic filariasis, caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and onchocerciasis (caused by Onchocerca volvulus) are neglected parasitic diseases of major public health...

Delayed treatment with the immunotherapeutic LNFPIII ameliorates multiple neurological deficits in a pesticide-nerve agent prophylactic mouse model of Gulf War Illness

Posted on Jul 10, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Residual effects of the 1990-1991 Gulf War (GW) still plague veterans 30 years later as Gulf War Illness (GWI). Thought to stem mostly from deployment-related chemical overexposures, GWI is a disease with multiple neurological symptoms with likely...

Belen Cassera named parasitology section editor for Current Clinical Microbiology Reports

Posted on Jul 8, 2021 in CTEGD Blog

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Last summer, biochemistry associate professor and Center for Tropical and Emerging Global Diseases member Belen Cassera was named the parasitology section editor for Current Clinical Microbiology Reports and has produced her first issue of reviews. Before former Editor-in-Chief...

Defense-Related Gene Expression Following an Orthotospovirus Infection Is Influenced by Host Resistance in Arachis hypogaea

Posted on Jul 5, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Planting resistant cultivars is the most effective tactic to manage the thrips-transmitted tomato spotted wilt orthotospovirus (TSWV) in peanut plants. However, molecular mechanisms conferring resistance to TSWV in resistant cultivars are unknown. In this study, transcriptomes of...

Mitochondrial Ca2+ and Reactive Oxygen Species in Trypanosomatids

Posted on Jul 4, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Significance: Millions of people are infected with trypanosomatids and new therapeutic approaches are needed. Trypanosomatids possess one mitochondrion per cell, and its study has led to discoveries of general biological interest. These mitochondria, as their animal counterparts, generate...

Serendipity leads UGA researcher into uncharted territory and a new NIH grant

Posted on Jul 2, 2021 in CTEGD Blog

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] [caption id="attachment_6563" align="aligncenter" width="600"] Ronald Drew Etheridge, UGA assistant professor of cellular biology, was awarded a five-year grant from the National Institutes of Health to continue his gene-editing work on Trypanosoma cruzi, the parasite that causes Chagas’...

Trainee Spotlight: Mayara Bertolini

Posted on Jun 23, 2021 in CTEGD Blog

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Mayara Bertolini is a third year Ph.D. trainee in the laboratory of Dr. Roberto Docampo. She has recently been awarded a predoctoral fellowship from the American Heart Association. Please tell us a little about yourself. I am from São...

EdU Incorporation To Assess Cell Proliferation and Drug Susceptibility in Naegleria fowleri

Posted on Jun 17, 2021 in publications

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]Naegleria fowleri is a pathogenic free-living amoeba that is commonly found in warm freshwater and can cause a rapidly fulminant disease known as primary amoebic meningoencephalitis (PAM). New drugs are urgently needed to treat PAM, as the...

Author: Donna Huber

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