Research Article Archives - Center for Tropical and Emerging Global Diseases

Trainee Adds New Tool to the Trypanosome Toolbox

Posted on Jul 19, 2018 in CTEGD Blog, Research Article

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[caption id="attachment_4660" align="aligncenter" width="600"] mCLING-staining of membrane (green) and DAPI staining of DNA (magenta) in trypanosomes in various life cycle stages. Flagella appear as tube-like structures along the length of the cell body. Nanotubes can be seen projecting outward from the periphery of the cells.[/caption] When...

Study reveals key cause of treatment failure in Chagas disease

Posted on Mar 29, 2018 in CTEGD Blog, Research Article

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[caption id="attachment_4579" align="aligncenter" width="600"] Photo by Peter Frey[/caption] Researchers at the University of Georgia have discovered that dormancy of the parasite Trypanosoma cruzi prevents effective drug treatment for Chagas disease, which kills more than 50,000 people each year in Central and South America and is a growing...

An ancient bacterial protein complex in human malaria parasites is essential for parasite growth

Posted on Nov 14, 2017 in CTEGD Blog, Research Article

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Several species of Plasmodium parasites cause malaria in humans and results in nearly 450,000 deaths annually. The deadliest of these species is Plasmodium falciparum. Unfortunately, it is also drug resistance to many of the currently available treatments. Vasant Muralidharan, assistant professor in the department of...

A Double Hit Strategy May Provide Better Treatment for Toxoplasmosis

Posted on Oct 23, 2017 in CTEGD Blog, Research Article

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[caption id="attachment_4361" align="aligncenter" width="602"] Zhu Hong Li is the lead author on the study.[/caption] Silvia Moreno and her research team at the University of Georgia's Center for Tropical & Emerging Global Diseases and Department of Cellular Biology provided evidence that it is possible to develop a...

The Cure for Malaria Could be in Your Backyard

Posted on Sep 8, 2017 in CTEGD Blog, Research Article

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Malaria is a mosquito-borne disease that has a disproportionate effect in poor and underdeveloped countries without access to western medicine. According to the WHO’s World Malaria Report, there were 212 million new cases of malaria worldwide in 2015 and an estimated 429,000 deaths. Malaria is caused by...

Oxidative Stress Contributes to Poor Pregnancy Outcomes During Placental Malaria

Posted on Jul 25, 2017 in CTEGD Blog, Research Article

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Julie Moore and her colleagues at the University of Georgia have determined that oxidative stress plays a role in the poor pregnancy outcomes that occur during placental malaria. Furthermore, they have identified the antioxidant tempol (TPL) as a potential therapeutic treatment....

UGA researchers report milestone in global fight against a major cause of diarrheal disease

Posted on May 31, 2017 in CTEGD Blog, Research Article

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[caption id="attachment_4014" align="aligncenter" width="1024"] Assistant research scientist Sumiti Vinayak, left, and Distinguished Research Professor Boris Striepen work together in Striepen's lab in the Coverdell Center for Biomedical and Health Sciences. Striepen and Vinayak are working together on vaccine and drug research for cryptosporidiosis, a disease...