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Tag: vaccine

Vaccine elicitation of HIV broadly neutralizing antibodies from genome-edited B cells in non-human primates and derived lymphoid organoids

Donna Huber on April 10, 2026

HIV broadly neutralizing antibodies (bnAbs) are promising reagents for prevention and therapy of disease; however, their elicitation is constrained by genetic limitations of the human B cell antigen-receptor (BCR) repertoire. Precision genome-editing offers a potential solution by enabling bnAb genes to be programmed into the BCR repertoire as IgH-modified B cells. Such cells can be …

Use of the Slow-Delivery Platform, VacSIM, Shapes the Host Immune Response to Increase Protection Against Influenza Infection

Donna Huber on August 30, 2025

Influenza virus is a leading cause of global morbidity and mortality due to acute lower respiratory infection, even with the widespread use of multiple licensed influenza vaccines. However, antigenic drift during influenza replication can cause vaccine-induced antibodies to poorly neutralize influenza virus, thereby reducing vaccine effectiveness. To help overcome this problem, we leveraged a hydrogel …

Chet Joyner receives $1.1 million grant to study malaria vaccine

Donna Huber on March 28, 2023

RESEARCH WILL BE IN COLLABORATION WITH YALE UNIVERSITY Chet Joyner, PhD, a faculty member in the Center for Vaccines and Immunology and the Center for Tropical and Emerging Diseases in the College of Veterinary Medicine (CVM) at the University of Georgia, is the recipient of a $1.1 million grant from Open Philanthropy to perform preclinical …

New method patented to provide increased vaccine efficacy

Donna Huber on November 13, 2018

by Donna Huber Vaccines can be an efficient and cost-effective method of preventing and treating pathogen-induced illnesses. As new pathogens appear and old pathogens re-emerge, improved vaccines are needed. For one emerging global disease, Chagas Disease, effective vaccine development has long been elusive. Now, Rick Tarleton, Regents’ Professor in the department of cellular biology, and former …