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Tag: trainees

Trainee Spotlight: Ruby Harrison

trainee Ruby Harrison

NIH T32 trainee Ruby Harrison is a co-advised by Drs. Michael Strand and Mark Brown in the UGA Department of Entomology. She received a Bachelor’s of Science in Entomology from the University of Wisconsin-Madison in 2012 and lived in Madison an additional two years working with mosquitoes as a research assistant. Before coming to UGA to begin my doctoral studies, she spent a year in Gabon, Africa, working as a tropical ecology field technician.

Ruby’s research focus

Ruby studies mosquito-microbiome interactions. Currently, she is investigating the influence of the gut microbiome on mosquito reproductive processes. She also plans to begin exploring the role of the mosquito microbiome in deterring pathogen infection in the very near future.

“I chose this research focus because I was inspired by the research of a former graduate student of Dr. Strand’s, Dr. Kerri Coon. Kerri pioneered fascinating work on the influence of the microbiota on development in mosquitoes in the immature (larval) stage,” said Ruby. “I saw an opportunity to extend her work, to observe if the same bacterial signal essential to larval development is recapitulated in any way in the adult stage.”

More broadly, she sees insect-microbe interactions as a promising field which may offer new solutions for mosquito population control and reduction of pathogen transmission.

NIH T32 Fellowship helps trainees achieve their goals

Ultimately, Ruby hopes to build a career as a vector biologist. For the capstone experience provided by the NIH T32 Training Grant, she is interested in returning to francophone West or Central Africa to work with mosquitoes in the field.

“I am truly grateful to receive the T32 pre-doctoral training fellowship, which presents me the opportunity to interact more closely with the CTEGD, opens doors for possible collaboration, and will help me to pursue my research goals,” said Ruby.

Trainee Spotlight: Msano Mandalasi

trainee Msano Mandalasi
Msano Mandalasi, a post-doctoral trainee in Chris West‘s laboratory, is originally from Malawi, (located in southeastern Africa) and obtained her bachelor’s degree in Chemistry from the University of Malawi. After graduation, she worked briefly for the University of Malawi and then came to the US to obtain a Master’s degree in Chemistry. Later, she enrolled in a doctoral graduate program at the University of Maryland Eastern Shore where she graduated in 2012. She spent two years teaching undergraduate Chemistry before deciding to get back into research. She joined Dr. West’s group while he was at the University of Oklahoma and moved with the lab to the University of Georgia.

Msano’s research focus

The focus of Msano’s project is on the role of prolyl hydroxylation and glycosylation of E3 Ubiquitin ligase on Toxoplasma growth.

With a research background mostly in chemistry and biochemistry, her graduate research introduced her to some aspect of parasitology working on Schistosome glycobiology. However, she did not have a strong background in molecular biology prior to joining the West lab. This current project merges glycobiology and molecular biology and also extends some parasitology studies, thus giving her the opportunity to learn molecular biology and parasitology to complement her chemistry background. A combination of this expert knowledge will benefit her to address the research objectives on her Toxoplasma project.

Capstone experience

Each T32 trainee is provided with the opportunity to complete a capstone experience at the end of their fellowship. This experience allows for an extended visit to a collaborator’s laboratory or travel to a scientific meeting where they present their research and interact with colleagues. Msano plans to use her capstone experience to give oral presentations at scientific meetings, to publish some of the studies conducted within this time period, and interact with other trainees in the program.

T32 fellowship helps trainees achieve their goals

“Through the funding provided by the T32 Training Grant, I will be able to address research questions that should lead to launching my own area of research,” said Msano.

Msano hopes to run her own independent research program in academia one day.

 

Support trainees like Msano Mandalasi by giving to the Center for Tropical & Emerging Global Diseases

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Trainee Spotlight: Evgeniy Potapenko

trainee Evgeniy Potapenko
Evgeniy Potapenko, a post-doctoral trainee in Roberto Docampo‘s laboratory, is from Kyiv, Ukraine. He obtained his MD from Bogomolets National Medical University (Kyiv) in 1997. Then he proceeded to earn a Ph.D. from Bogomoletz Institute of Physiology (Kyiv) in 2004. Later he conducted postdoctoral training in Europe at the University of Goettingen and the University of Birmingham and also in the USA at Augusta University before coming to the University of Georgia. Evgeniy is a recipient of the Center’s NIH funded T32 Training Grant for Interdisciplinary Parasitology, Vector Biology, and Emerging Diseases.

Evgeniy’s research focus

Generally, Evgeniy is interested in mechanisms of transmembrane transport and their role in parasite homeostasis. His current project goal is to characterize how the IP3R function modulated within the Trypanosoma brucei, the parasite that causes African Sleeping Sickness, acidocalcisomes where it resides and how deregulation of this process can contribute to cell death. This research topic addresses poorly studied mechanisms of parasite physiology and has the potential importance of discovering new methods of patient treatment.

Capstone Experience

Each T32 trainee is provided with the opportunity to complete a capstone experience at the end of their fellowship. This experience often involves an extended visit to a collaborator’s laboratory to learn new techniques or to an endemic country to see how their research connects to actions being taken in the field.

“I hope to expand my expertise in both electrophysiology and cellular biology approaches, which will allow me to conduct independent research,” said Evgeniy.

T32 fellowship helps trainee achieve goals

“T32 is a unique possibility to prepare me for an independent research career,” said Evgeniy. “It gives great tools to achieve this goal.”

Trainee Spotlight: Manuel Fierro

trainee Manuel Fierro

Manuel Fierro is a pre-doctoral trainee in Vasant Muralidharan’s Laboratory. He is originally from Ecuador. His family moved to the US when he was 9 years old, and he has lived in Georgia ever since. Manuel received his Bachelor of Science degree in Cellular Biology from the University of Georgia in 2014. He is a recipient of the Center’s NIH funded T32 Training Grant for Interdisciplinary Parasitology, Vector Biology, and Emerging Diseases.

Manuel’s research focus

Manuel’s project deals with understanding how calcium is regulated in the endoplasmic reticulum of Plasmodium falciparum, the parasite that causes malaria.

“My undergraduate training was in Dr. Silvia Moreno’s lab studying calcium signaling in Toxoplasma gondii and I wanted to answer the same type of questions in Plasmodium,” said Manuel.

Capstone Experience

Each T32 trainee is provided with the opportunity to complete a capstone experience at the end of their fellowship.

“My home country of Ecuador is approaching elimination of malaria,” said Manuel, “and I would like to work with some of the researchers in the field there who track populations of infected mosquitoes as well as monitor cases of infection in humans.”

T32 Fellowship helps trainee achieve goals

“I truly enjoy working in a lab, but it is not the same as experiencing what diseases are like in the real world,” said Manuel. “This fellowship will help me expand my understanding of malaria by giving me the opportunity to see it in a different setting.”

Manuel is currently considering a career in industry, but he is open to staying in academia.

 

Support trainees like Manuel Fierro by giving to the Center for Tropical & Emerging Global Diseases

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UGA receives $1.25 million for training of tropical, emerging global diseases researchers

trainee Charles Rosenberg

Athens, Ga. – The University of Georgia’s Center for Tropical and Emerging Global Diseases was awarded $1.25 million by the National Institutes of Health to continue training graduate and postdoctoral students over the next five years who can help address the growing threats of parasitic diseases.

Every year, diseases caused by protozoan and helminth parasites are responsible for more than a million deaths and cause hundreds of millions more cases of severe or subtle morbidity due to chronic infections lasting years.

“The University of Georgia is uniquely positioned as a training ground for the next generation of parasitology and tropical diseases researchers,” said Silvia Moreno, a professor of cellular biology in the Franklin College of Arts and Sciences and co-director of the center’s T32 trainee program.

The internationally recognized research center brings together the largest number of laboratories in the U.S. that collectively conduct research on the full gamut of parasite diseases. These diseases are highly prevalent in sub-Saharan Africa, South America and Asia. Often they are the consequence and cause of poverty. They also are increasingly emerging or re-emerging in the U.S. and other industrialized nations.

The CTEGD training program is currently in its 10th year. Past trainees have gone on to successful careers as staff scientists at the Centers for Disease Control and Prevention and as faculty, postdoctoral scholars or medical and veterinary scientists at leading universities and research institutes.

“The breadth and culture of our program instills trainees with the ability to not only translate basic scientific findings into tool development and the implementation of interventions, but also to identify and formulate fundamental research questions beyond the context of parasitic disease itself,” Moreno said.

“This program is very attractive to students,” said Boris Striepen, Distinguished Research Professor of Cellular Biology in the Franklin College and co-director of the training grant. “We have had many more strong candidates than training slots.”

To address this issue, the new NIH award will double the number of postdoctoral trainees from one to two each year, and matching funding from UGA’s Office of the Vice President for Research will support two predoctoral trainees in addition to the three graduate students supported by the training grant each year.
“This institutional matching support is tremendously important when competing for NIH training grants,” said Dan Colley, CTEGD director, who was the T32 training grant program director for its first 10 years.

Trainees in the program build upon their background in biomedical sciences through specialized courses and research mentored by one or more CTEGD faculty. The program is unique in that students can also broaden their perspective on the global aspects of parasitic diseases through a capstone experience, which typically takes students away from the UGA campus for four to eight weeks. Many of the previous trainees have conducted field studies in a disease-endemic country.

“My capstone experience in Kenya provided an exceptional opportunity to gain experience both working in the field and in a laboratory in a developing setting,” said Briana Flaherty, a doctoral student in the CTEGD and the department of infectious diseases. “This short time has had a profound impact on my future interests and career goals.”

The many international collaborations of the center’s faculty provide a wide variety of opportunities to the trainees. Over the last nine years, graduate students have worked in Haiti, Tanzania, Argentina, Thailand and Kenya. The Office of the Vice President for Research also has committed funds over the next five years to assist in the provision of these experiences on the T32 training grant.

“We in CTEGD are extremely pleased that NIH has seen fit to fund this T32 training grant for an additional five years,” Colley said. “It is an investment in our new program directors, Drs. Striepen and Moreno, and in CTEGD’s commitment to high-quality training of the next generation in this important area of parasitic disease-related research.”

The grant funding is provided under NIH award number 3T32AI060546.

UGA Center for Tropical and Emerging Global Diseases
The University of Georgia Center for Tropical and Emerging Global Diseases draws on a strong foundation of parasitology, immunology, cellular and molecular biology, biochemistry and genetics to develop medical and public health interventions. Established in 1998, the center promotes international biomedical research and educational programs at UGA and throughout Georgia to address the parasitic and other tropical diseases that continue to threaten the health of people throughout the world. For more information, see http://ctegd.uga.edu/.

Writer: Donna Huber
Contact:Boris Striepen