Tag: diagnostic

From Target Product Profiles (TPPs) to Target Specimen Profiles (TSPs): A New Concept in Infectious Disease Biobanking for Diagnostic Applications

Donna Huber on June 13, 2025

A target specimen profile (TSP) corresponds to the required characteristics of the specimen panels needed to demonstrate that a diagnostic kit meets the target product profile (TPP). TSPs can guide biobanks in the prospective collection of sample panels to support the development and validation of diagnostics.

Fay Betsou, Warren Fransman, Patrick Lammie. Diagnostics (Basel). 2025 Jun 13;15(12):1503. doi: 10.3390/diagnostics15121503.

A pathway for skin NTD diagnostic development

Donna Huber on November 25, 2024

Fig 1. A typical journey for a skin NTD patient.

The present document outlines the next steps recommended by the Skin NTDs subgroup of the DTAG to operationalise individual disease TPPs and to advance the NTD road map approach of scaling up integrated approaches to skin NTDs.

Michael Marks, Sundeep Chaitanya Vedithi, Wendy W J van de Sande, Bruno Levecke, Anthony W Solomon, Kingsley Asiedu, Camilla L Ducker, Patrick Lammie, Daniel Argaw Dagne, Isra Cruz; WHO Diagnostic Technical Advisory Group on Neglected Tropical Diseases. PLoS Negl Trop Dis. 2024 Nov 25;18(11):e0012661. doi: 10.1371/journal.pntd.0012661. eCollection 2024 Nov.